| Saturday, 1/22/2022 at 4:30 PM | CINCINNATI (11-7) at TENNESSEE (12-5) | |
| Expanded Matchup | FoxSheet | Results | Offensive Statistics | Defensive Statistics |
| Teams | Line | PF | PA | SU | ATS | O/U/P | TO | RY | RYPA | PY | PYPA | RY | RYPA | PY | PYPA |
| 301: CINCINNATI | 47.5 | 27.0 | 21.9 | 11-7 | 11-7-0 | 8-10-0 | +2 | 101.4 | 4.0 | 257.1 | 7.9 | 102.5 | 4.4 | 250.2 | 6.6 |
| 302: TENNESSEE | -4.0 | 24.6 | 20.8 | 12-5 | 10-7-0 | 8-9-0 | -3 | 141.4 | 4.4 | 201.1 | 6.4 | 84.6 | 3.9 | 245.2 | 6.6 |
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| Saturday, 1/22/2022 at 8:15 PM | SAN FRANCISCO (11-7) at GREEN BAY (13-4) | |
| Expanded Matchup | FoxSheet | Results | Offensive Statistics | Defensive Statistics |
| Teams | Line | PF | PA | SU | ATS | O/U/P | TO | RY | RYPA | PY | PYPA | RY | RYPA | PY | PYPA |
| 303: SAN FRANCISCO | 48.0 | 25.0 | 21.2 | 11-7 | 10-8-0 | 8-10-0 | -5 | 129.7 | 4.3 | 244.1 | 8.2 | 102.1 | 4.0 | 209.1 | 6.4 |
| 304: GREEN BAY | -6.0 | 26.5 | 21.8 | 13-4 | 12-5-0 | 8-9-0 | +13 | 111.8 | 4.3 | 254.9 | 7.3 | 109.1 | 4.7 | 219.3 | 6.2 |
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| Sunday, 1/23/2022 at 3:00 PM | LA RAMS (13-5) at TAMPA BAY (14-4) | |
| Expanded Matchup | FoxSheet | Results | Offensive Statistics | Defensive Statistics |
| Teams | Line | PF | PA | SU | ATS | O/U/P | TO | RY | RYPA | PY | PYPA | RY | RYPA | PY | PYPA |
| 315: LA RAMS | 48.5 | 27.4 | 21.3 | 13-5 | 9-9-0 | 9-8-1 | +4 | 101.3 | 4.0 | 270.9 | 7.8 | 100.8 | 3.9 | 235.1 | 6.4 |
| 316: TAMPA BAY | -3.0 | 30.1 | 20.4 | 14-4 | 10-8-0 | 9-9-0 | +13 | 98.7 | 4.3 | 304.0 | 7.1 | 92.7 | 4.4 | 239.2 | 6.0 |
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| Sunday, 1/23/2022 at 6:30 PM | BUFFALO (12-6) at KANSAS CITY (13-5) | |
| Expanded Matchup | FoxSheet | Results | Offensive Statistics | Defensive Statistics |
| Teams | Line | PF | PA | SU | ATS | O/U/P | TO | RY | RYPA | PY | PYPA | RY | RYPA | PY | PYPA |
| 317: BUFFALO | 55.5 | 29.4 | 17.0 | 12-6 | 11-6-1 | 9-9-0 | +10 | 132.4 | 4.9 | 254.9 | 6.8 | 108.6 | 4.2 | 165.9 | 5.3 |
| 318: KANSAS CITY | -2.5 | 29.0 | 21.4 | 13-5 | 9-9-0 | 11-7-0 | +3 | 114.5 | 4.5 | 286.8 | 7.2 | 114.2 | 4.7 | 248.6 | 6.8 |
