| | Statistic | FOR | OPP |
| Total Yards per Game | 316.0 | 334.4 |
| Rushing YDS per ATT | 3.3 | 4.7 |
| Passing YDS per ATT | 6.9 | 6.3 |
| Passing Comp % | 0.635 | 0.667 |
| Total YDS per Play | 5.5 | 5.4 |
| Total YDS per Point | 13.9 | 17.2 |
|
| Injury |
| [WR] Anthony Gonzalez injured last game, "?" - Head - 10/07/08 |
| [CB] Marlin Jackson is "?". - Ankle - 10/09/08 |
| [DE] Dwight Freeney injured last game, "?" - Hamstring - 10/09/08 |
| [DE] Robert Mathis is "?". - Undisclosed - 10/09/08 |
| [S] Bob Sanders is expected to miss 4-6 weeks. - Ankle - 09/17/08 |
| [CB] T.J. Rushing IR - Knee - 08/25/08 |
| [CB] Kelvin Hayden is downgraded to doubtful - Knee - 10/08/08 |
| [G] Dan Federkeil missed last game, "?" - Ribs - 10/05/08 |
| [OG] Ryan Lilja expected to miss at least six weeks. - Knee - 08/09/08 |
| [LB] Tyjuan Hagler expected to miss at least six weeks. - Pectoral - 08/02/08 |
| [WR] Roy Hall missed last game, "?" - Knee - 10/03/08 |
| [DE] Mike Pollak expected to miss at least 4 weeks. - Knee - 09/10/08 |
| [CB] Michael Coe IR - Knee - 08/13/08 |
