Kickoff: Monday, 8:30 p.m. ET
Line: Philadelphia -6.5, Total: 48

The struggling Panthers are in a must-win situation when they visit the Eagles on Monday night.

Philadelphia will be without starting QB Nick Foles (collarbone) indefinitely, leaving Mark Sanchez as the No. 1 signal caller. Sanchez helped the Eagles beat the Texans 31-21 in Houston last week, which made them 3-1 (SU and ATS) in their past four games. Carolina is going the opposite direction with four straight games without a win (0-3-1 SU), including a lopsided 28-10 home loss to the Saints last Thursday. The Panthers and Eagles have met just eight times since Carolina entered the league in 1995, with Philly holding the 5-3 advantage (SU and ATS). But in the most recent meeting in 2012, Cam Newton threw for 306 yards and two touchdowns in a 30-22 road victory for the Panthers. Carolina is 20-8 ATS after trailing in its previous game by 14 or more points at the half since 1992. The team is also 24-10 ATS after scoring 14 points or less in two straight games in that time. Philadelphia, meanwhile, is 159-125 ATS against conference opponents since 1992. S Thomas DeCoud (hamstring) and CB Bene Benwikere (ankle) are listed as questionable for the Panthers, as are three offensive linemen -- G Trai Turner (knee), OT Byron Bell (elbow) and G Amini Silatolu (calf). The Eagles are also thin on their offensive line with G Todd Herremans (bicep) landing on IR this week while G Evan Mathis (knee) is questionable. They also have two key defenders with injuries, as LB DeMeco Ryans suffered a season-ending torn Achilles last week and S Nate Allen (hamstring) is questionable.

Can the Eagles win comfortably over the struggling Panthers on Monday night? For the answer, connect to NFL Best Bets for all the StatFox Experts picks throughout the 2014 regular season and playoffs. The experts have remained hot over the past seven weeks, combining for a 57% ATS mark (62-46). StatFox Scott is 71% ATS (20-8) in Best Bets during this timeframe, and 64% ATS (23-13) on the season. StatFox Dave is 60% ATS (18-12) in Best Bets during these seven weeks to improve to 55% ATS (22-18) on the season, while StatFox Brian has gone 56% ATS (14-11) in NFL Best Bets since Week 3, and continues to roll in NFL Totals with a stellar 70% record (19-8) for the season.

Carolina has really faltered recently, but needs to move past that and pick up a win in Philadelphia on Monday. QB Cam Newton (1,794 pass yards, 8 TD, 5 INT) is coming off one of the worst games of his career, completing only 10-of-28 passes for 151 yards, no touchdowns and one interception at home against a miserable New Orleans defense. He should, however, have a great chance to turn things around against a Philadelphia defense that is allowing 256.3 passing yards per game (22nd in NFL). WR Kelvin Benjamin (40 rec, 589 yards, 5 TD) and TE Greg Olsen (45 rec, 539 yards, 5 TD) will constantly be open over the middle of the field against this defense and Newton will need to deliver more accurate passes, as he was overthrowing receivers consistently last game. One issue this team is having is in the ground game, as the Panthers are rushing for just 94.7 yards per contest (26th in NFL), which is giving teams the ability to focus strictly on stopping Newton and this passing offense. Defensively, Carolina has also struggled in both aspects of the game. They are allowing 246.2 passing yards per game (17th in NFL) and 131.9 rushing yards per game (26th in NFL). They do have a good chance to turn things around as they’ll face an offense led by a backup quarterback.

Eagles QB Mark Sanchez has been eager to get another chance at starting in the NFL and with Nick Foles’ injury, he has a golden opportunity to turn his career around by running a very potent offensive team. Sanchez threw for 202 yards (9.2 YPA) with two touchdowns and two interceptions while picking up a victory for the Eagles last week against the Texans. His first start will come against a below-average passing defense. RB LeSean McCoy (622 rush yards, 1 TD) has had a down year for his standards, but he has heated up with 116.3 rushing yards per game in the past three weeks. His workload should increase with the Eagles now starting a quarterback who is less familiar with their system. One player who has completely stood out on this team is WR Jeremy Maclin (45 rec, 790 yards, 8 TD). He has been on a tear recently, catching two touchdowns in each of the past two games with 150+ yards in both. It will be interesting to see if he can keep up his production with Sanchez at quarterback, but Maclin did catch all four Sanchez targets for 88 yards and a touchdown last week. This defense will need to improve as they get closer to the playoffs, as their play can get very sloppy at times. For the season Philly is allowing 116.9 rushing YPG (20th in NFL) and 256.3 passing YPG (22nd in league). Monday will be a good chance for this team to cause some turnovers with Newton at quarterback for the Panthers.