Kickoff: Sunday, 4:25 p.m. ET
Line: Arizona -6.5, Total: 47.0

Offense will be at a premium when the Seahawks and Cardinals, two of the league’s best defenses square off in Week 17 with playoff seeding on the line.

The Cardinals have already clinched at least the #2 seed, but can still earn home-field advantage through the NFC playoffs with a victory and a loss by the Panthers. The Seahawks have also clinched a wild card spot and will play their first NFC playoff game away from Seattle since January 2013 in two week’s time; whether that game is at Green Bay, Minnesota, or Washington is still to be determined. Seattle (9-6 SU, 7-7-1 ATS) fell to St. Louis for the 2nd time this season, 23-17, ending their five game SU and ATS winning streak, despite holding their opponent below 250 total yards for the 3rd time in their last four games. The Seahawks rushed for just 60 yards, their first game under 100 yards this season, and finished the game with a season-worst -3 TO margin. Arizona (13-2 SU, 9-6 ATS) stated their case as the team to beat in the NFC with a 38-8 thumping of Green Bay, their 9th straight win. The Cardinals outgained the Packers by more than 200 total yards, recorded nine sacks of Aaron Rodgers and back-up Scott Tolzien -- the most sacks by the Cardinals in a game in 29 years -- and returned two Packers’ fumbles for touchdowns. Despite entering as the underdog, trends for the game skew slightly in Seattle’s favor. Russell Wilson is 44-26 ATS in his career, including a 10-2 ATS mark in his last 13 games as an underdog (6-2 ATS in his last nine games as a road underdog). Carson Palmer is 40-36 ATS in his last 78 games, including a 28-22 ATS mark in his last 52 games. As the favorite, Palmer is just 19-19 ATS in his last 39 games, and even worse at home, where’s he’s just 11-15 ATS in his last 26 games. Pete Carroll is 62-41 ATS during his tenure as Seattle head coach, including a 50-29 mark vs. the rest of the NFC (23-13 vs. the rest of the NFC West); Carroll is also 25-15 ATS as an underdog. Bruce Arians is 30-17 ATS as Arizona head coach, 25-11 vs. the NFC. Seattle is dealing with some notable injuries on both sides of the ball: TE Luke Willson (concussion), T Russell Okung (calf), DT Jordan Hill (toe), and S Kam Chancellor (tailbone) are all questionable for Sunday’s regular season finale. For the Cardinals, DE Josh Mauro is questionable with a calf injury.

Seattle enters Week 17 allowing 295.9 total YPG (2nd in league), 85.3 of those yards coming by way of the run (3rd in league) and 210.6 of those yards coming by way of the pass; all of those marks are best among NFC teams, as is their 18.1 PPG allowed (3rd amongst all teams). The defense has also excelled in getting off the field in late down situations. Teams are converting on only 33.9% of 3rd downs and 16.7% of 4th downs against the Seahawks’ defense; those marks ranks 5th and 1st in the league, respectively. Russell Wilson and Doug Baldwin will also have plenty of confidence heading into this one. The Seahawks were embarrassed a week ago, but the two have connected for 11 touchdowns over the past five weeks.

Seattle’s high ranking defense will have their hands full with an Arizona offense coming in averaging 420.1 total YPG (1st in the league), courtesy of a 3rd ranked pass attack and 6th ranked run game; both of those ranks are based on YPG averages. The Cardinals, averaging a league-best 32.3 PPG, are also just 17 points shy of their first 500-point season in franchise history. Arizona not only has Carson Palmer and a high-powered passing offense, but the team is also running the ball with a ton of success thanks to David Johnson. The rookie has not allowed this running game to skip a beat following the loss of Chris Johnson. The Cardinals will need a balanced attack in order to beat Seattle in this one.