ORCHARD PARK, N.Y. (AP) -Texans tight end Owen Daniels sprained his right knee in the first quarter of Houston's game at the Buffalo Bills.

Daniels was hurt during Houston's second possession Sunday. It's unclear how he was hurt, the player going down near the line of scrimmage before Matt Schaub underthrew a pass intended for Kevin Walter.

Daniels lay on the field for several minutes before being helped up by trainers. He was unable to put much weight on his right leg as he was escorted to the sideline, where he had a bag of ice wrapped around his knee. He entered the game leading NFL tight ends with 497 yards receiving and ranked second with five touchdowns.

Bills starting right tackle Jamon Meredith was carted off after hurting his right leg.