PHILADELPHIA (AP) -Score the first round of the New York-Philly twinbill in favor of the Eagles by brutal knockout.

Donovan McNabb threw three touchdown passes and DeSean Jackson had another big TD catch as the Philadelphia Eagles took a 40-17 win over a mistake-prone Eli Manning and the New York Giants on Sunday.

The game was just the appetizer in a marathon day in the NY-Philadelphia rivalry. The Yankees and Phillies were set for the first pitch of Game 4 of the World Series across the street only hours after the Eagles' rout ended.

The Eagles (5-2) remained undefeated in the division and host Dallas next week.

New York (5-3) has lost three straight games after starting the season 5-0 for the first time since 1990.