LOUISVILLE, Ky. (AP) - The No. 16 Louisville Cardinals know that South Florida's mission on Saturday is turn to turn its season around with a big win.

The Cardinals know firsthand how a key victory can turn things around; they just don't want the Bulls doing it at their expense.

A senior-laden South Florida squad that was expected to challenge for the Big East championship has lost four straight since a 2-0 start - leaving the Bulls at a crossroads coming out of a bye week.

Meanwhile, Louisville (6-0, 1-0) returns home from a 35-day absence with its best start since 2006 and hungry to follow up last week's conference win at Pittsburgh.

Keeping the Cardinals focused on continuing their roll is their memory of being in the Bulls' position a year ago.