GLENDALE, Ariz. (AP) - On an almost perfect Monday night for Alex Smith, the San Francisco 49ers flexed their NFC West dominance with a 24-3 flattening of the Arizona Cardinals.

Smith completed 18 of 19 passes for 232 yards and three touchdowns two to Michael Crabtree and one to Randy Moss, as San Francisco (6-2) opened a two-game lead in the division and sent Arizona (4-4) to its fourth straight lost.

Smith's only incompletion was dropped by a wide-open receiver.

Smith was 14 of 15 and for 146 yards and two touchdowns, both to Crabtree, to help the 49ers build a 17-0 halftime lead.

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