English Premier League Week 2 Kick-off: Friday, 3:00 p.m. ET Line: Manchester United -227, Southampton +650, Tie +325, Total: 2.5Manchester United welcomes Southampton to Old Trafford in this season’s first Friday match. Manchester United opened its campaign with a 3-1 victory at Bournemouth, and the club now returns home in a tricky fixture against Southampton. David De Gea will start in net for the Red Devils, and although Chris Smalling will be available, manager Jose Mourinho will likely stick with the same back line from the opening match, which featured Antonio Valencia, Daley Blind, Eric Bailly, and Luke Shaw. In midfield, record summer signing Paul Pogba has declared himself fit, and he could start alongside Ander Herrera. Anthony Martial and Juan Mata will likely play on the wings, with Henrikh Mkhitaryan also an option, and Wayne Rooney will play behind striker Zlatan Ibrahimovic. Fraser Forster will start in goal for the Saints, and Cedric Soares, Maya Yoshida, Jose Fonte, and Virgil Van Dijk should compose the defensive unit. Oriol Romeu, Steven Davis, James Word-Prowse, and Dusan Tadic could start in midfield, with Shane Long in Nathan Redmond in attack. With two solid defenses, under 2.5 goals should be scored. Those goals will belong to Manchester United in a 2-0 victory for the home side.
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